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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Karen Jung

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2 papers indexed here

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Open access Sep 2026

Degradomic and Transcriptomic Profiling Reveals Pleiotropic Roles of Extracellular Granzyme B in Scarring and Fibrosis.

Granzyme B (GzmB) is a serine protease traditionally recognized for its role in lymphocyte-mediated apoptosis. In specific conditions, GzmB accumulates in the extracellular milieu and retains its proteolytic activity, cleaving extracellular proteins thereby contributing to disease progression. Nevertheless, pathologica...

A. Aubert, A. Prudova, Jeffrey S. Tang et al. · 0 citations
Review Open access Aug 2026

Granzymes in Neuroinflammation and Neurodegenerative Diseases

Neuroinflammation is a central driver of numerous neurological disorders. While granzymes have classically been studied as cytotoxic effector molecules secreted from immune cells along with the pore-forming molecule, perforin, accumulating evidence suggests that these serine proteases also play roles in non-cytotoxic...

Daniele P. Ferrari, J. Sidhu, Karen Jung et al. · 0 citations

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