Biofilm dispersion by Pseudomonas aeruginosa requires relocation of BdlA to drive a switch in motility by dispersed cells
The regulatory mechanism of how Pseudomonas aeruginosa biofilm cells switch their motility phenotype to disperse from biofilms is explored, revealing a new regulatory mechanism in which dispersion signals drive BdlA relocation, activate DipA’s phosphodiesterase activity, lower cyclic di-GMP, and elevate fliC expression...