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Karthik Mangu

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#federated learning Review Open access Oct 2026

Artificial Intelligence in genetic healthcare: toward adaptive and systems-level genomic medicine

Artificial intelligence is reshaping genetic healthcare through increasingly sophisticated approaches to variant interpretation, disease prediction, biomarker discovery, gene editing, and precision therapeutics. Yet these applications remain fragmented, often treating genomic and clinical information as static observat...

Ishanvi Tupili, Deekshitha Ravipati, Karthik Mangu et al. · 0 citations
Review Jul 2026

CRISPR-Cas9-based therapies for Huntington’s disease and Friedreich’s ataxia: mechanisms, advances, and future perspectives

Current CRISPR therapeutic strategies for HD and FRDA are examined, including allele-specific editing, transcriptional suppression, repeat excision, epigenetic reactivation, and emerging precision editing approaches such as base editing and prime editing.

Abha Ravikumar Mundada, Amogh Reddy Badikol, Karthik Mangu · 0 citations

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