Sep 2026
Rewiring the ribosome to translate proteins encoded in its own RNA.
These findings establish the mechanistic feasibility of a ribosome translating its own rRNA in vivo and in vitro, offering a versatile platform for orthogonal protein production and insights into the origin of translation.
Kasra Alizadeh, D. Klepacki, N. Vázquez-Laslop et al.
· Nature · 0 citations