Alcohol dehydrogenase D from Pyrococcus furiosus is a thermostable rare earth element binding enzyme: Characterization of metal-binding and chromatographic separation of critical materials.
This work investigated and biochemically characterized the REE-binding properties of alcohol dehydrogenase D, a thermostable aldo-keto reductase from Pyrococcus furiosus, and identified and characterized a high-affinity REE binding site with low micromolar affinity, consistent with bioavailable free REE concentrations...