Beyond B cells: T and Innate Immune Mechanisms of Autoimmunity in Common Variable Immunodeficiency
Common variable immunodeficiency (CVID) is the most prevalent symptomatic primary immunodeficiency, affecting approximately 1 in 25 000–50 000 individuals. Although classically characterized by hypogammaglobulinemia and recurrent bacterial infections, over 50% of patients develop non-infectious complications that const...