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Katelyn N. Ayers

1 paper indexed here

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Open access Aug 2026

PD-1 regulates CD4+ T cell-mediated CD8+ T cell responses in the brain to balance viral control and neuroinflammation

Programmed cell death protein 1 (PD-1) is expressed by T cells during progressive multifocal leukoencephalopathy (PML), a life-threatening brain disease caused by the human-only JC polyomavirus (JCPyV). PD-1 checkpoint immunotherapy has benefited some PML patients, but reasons for its variable outcomes are unclear. Usi...

Arrienne B. Butic, E. Afanasiev, Samantha A. Spencer et al. · 0 citations

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