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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Katherine García

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Open access Sep 2026

The gut-brain axis as a therapeutic target in alcohol use disorder: dietary fiber, intestinal barrier integrity, and neuroinflammatory mechanisms underlying depression

This Perspective proposes that intestinal barrier dysfunction represents an actionable upstream mechanism linking alcohol-induced gut dysbiosis with neuroinflammation, depression, and relapse vulnerability, and highlights dietary fiber supplementation as a physiologically grounded, accessible nutritional strategy to en...

Diliana Pérez-Reytor, Katherine García, Ítalo M. Urrutia et al. · 0 citations
Review Jul 2026

The Role of Microbiota, Gut Integrity, and Neuroinflammation in Relapse Vulnerability in Alcohol Use Disorder.

This narrative review integrates mechanistic and translational evidence linking gut dysbiosis, intestinal barrier dysfunction, systemic inflammation, and neuroimmune activation to relapse vulnerability in AUD by situating relapse within an integrated gut-brain framework.

Diliana Pérez-Reytor, Eduardo Isla, Ítalo M. Urrutia et al. · 1 citation

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