Computational Analysis of Peptide Binding on Dengue-Associated Host Proteins POLR2A and Elongin C: Network Pharmacology, Molecular Docking, and Dynamics Simulation Insights
A protein-protein interaction network from the genes associated with the dengue infection was constructed and proteins were ranked by the topological centrality to identify hub regulators and validated POLR2A and ELOC as hub genes in the transcriptional regulation network associated with dengue.