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Author

Kathrin Halter

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Open access Oct 2026

The tRNA-Modification Geranyl-2-Thiouridine Enables RNA-Lipid Association.

The packaging of RNA in lipid nanoparticles for protection and delivery was key for the development of mRNA vaccines and therapeutics. Formulation requires the addition of a variety of lipids (including cationic) in high amounts to form complexes with the negatively charged RNA. While this approach was successful for t...

Johannes Singer, Kathrin Halter, Chun-Yin Chan et al. · 0 citations
Review Open access Aug 2026

Unmasking the modified small non-coding RNome: detection strategies for RNA modifications

Current strategies for detecting and mapping RNA modifications in the small RNome include demodification-based sequencing approaches for heavily modified RNAs, targeted chemical and enzymatic methods for site-specific mapping, and emerging direct RNA sequencing technologies that allow analysis of native molecules witho...

Bennett Henzeler, Kathrin Halter, Özge Simsir et al. · 0 citations

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