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Author

Kavita M. Dhodapkar

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Open access Aug 2026

B-cell depletion improves therapeutic index of combination checkpoint blockade in patients with advanced melanoma.

BACKGROUND Combined checkpoint blockade (CCB) of programmed-death-1 (PD-1) and cytotoxic-T-lymphocyte-associated protein-4 (CTLA-4) is highly active in melanoma but limited by significant morbidity from immune-related adverse events (irAEs). Effective strategies to prevent CCB-mediated irAEs are lacking. METHODS Pati...

Kavita M. Dhodapkar, Antonio Matera, Alyssa M. Duffy et al. · 0 citations

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