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Author

Kayla Schwartz

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Open access Sep 2026

Plasma and cerebrospinal fluid proteomics reveal distinct patterns of senescence and neuropathology in aging rhesus macaques.

Aging is the primary risk factor for neurodegenerative disease, yet the protein signatures that distinguish physiological brain aging from pathological decline remain incompletely defined in translational models. Using the targeted NULISAseq proteomic platform, we profiled cerebrospinal fluid (CSF) and plasma from 66 r...

Giovanne B. Diniz, Kayla Schwartz, Carissa T. Erices et al. · 0 citations
Open access Aug 2026

Loss of neuronal population organization links pathology to behavior in a model of Alzheimer’s disease

This work uses an adeno-associated virus-induced longitudinal macaque model of Alzheimer’s disease to examine early changes in behavior, neuronal population activity, and pathology and suggests that early disease is accompanied by a progressive loss of coordinated population activity.

Douglas A. Ruff, Drew E. G. Sheets, Ramanujan Srinath et al. · 0 citations

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