Open access
Aug 2026
Methylglyoxal mildly impairs spatial memory and reduces expression of excitatory synaptic genes in the hippocampus of male mice
Findings identify learning‐associated excitatory synaptic genes as targets of chronic MG exposure and position MG as a candidate factor linking the diabetic metabolic state to hippocampal synaptic and cognitive alterations.
Akane Nakao, Takumi Yokokawa, Fuminori Okazaki et al.
· Physiological Reports · 0 citations