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Kazuyuki Takata

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Jul 2026

Down syndrome-associated trisomic chromosomal regions modify amyloid-β accumulation and cause early death in a mouse model of aspects of Alzheimer's disease

The trisomic region in Ts1Kei mice is suggested to harbor genes associated with decreased Aβ accumulation, and the trisomic region in Ts1Rhr mice contains genes suppressing sudden death in APPswe/PS1dE9 mice.

Keiichi Ishihara, Haruka Yasui, Koki Harada et al. · 1 citation
Review Open access Jul 2026

Neurotheranostics in Alzheimer's Disease: Current concepts and experimental strategies.

Recent advances in neurotheranostic approaches for AD are summarized and emerging molecular probes, low-molecular-weight compounds, and delivery technologies are highlighted, including contributions from the authors' studies.

Daijiro Yanagisawa, Takashi Ohgita, Hidekazu Kawashima et al. · 1 citation

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