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Open access Oct 2026

A grayscale ultrasound-based two-stage deep learning framework for automatic segmentation and benign-malignant differentiation of subpleural pulmonary lesions

Lung cancer is one of the most lethal malignancies globally. However, accurately differentiating subpleural malignant lesions from benign infectious conditions via grayscale ultrasound remains difficult due to operator subjectivity. We developed and validated a two-stage deep learning framework for automated lesi...

Qian-Peng Ma, Tian-Xi Liang, Jia-Wei Yi et al. · 0 citations
Oct 2026

CEUS- versus US- and CT-guided Biopsy for Subpleural Lung Lesions: A Prospective, Multicenter Randomized Controlled Trial.

BACKGROUND Ultrasound (US)-guided percutaneous lung needle biopsy (PLNB), the guideline-recommended approach for subpleural lung lesion (SLL) diagnosis, requires comparison with CT-guided biopsy based on high-level evidence clinical studies. RESEARCH QUESTION Is US-guided PLNB superior to CT-guided biopsy in diagnost...

Ke Bi, Meng-Jun Shen, Dong Xu et al. · 0 citations

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