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Aug 2026

Does there exist a bidirectional association between insulin resistance and depressive symptoms in middle-aged and older adults?

Among middle-aged and older adults, a unidirectional within-person association was observed between IR and depressive symptoms, whereby elevations in IR above an individual's usual level were associated with more severe depressive symptoms.

Liying Jing, Yi-Xuan Fan, Xiaofan Wu et al. · 0 citations
Open access Aug 2026

Joint trajectories of frailty and depressive symptoms and risk of incident osteoarthritis in middle-aged and older adults

Background Frailty frequently overlaps with depressive symptoms among middle-aged and older adults. However, it remains unclear how these two conditions develop concurrently over time and whether their combined longitudinal patterns are associated with the subsequent onset of osteoarthritis (OA). This study aimed to ch...

Ting-Jie Chang, Zhipeng Qin, Feng Zhao et al. · 0 citations

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