Case Report: dupilumab for severe pruritus in pediatric recessive dystrophic epidermolysis bullosa—a longitudinal clinical assessment and literature review
Recessive dystrophic epidermolysis bullosa (RDEB) results from biallelic COL7A1 variants and causes trauma-induced blistering, scarring, and progressive extracutaneous complications. Severe pruritus may intensify skin injury through an itch-scratch cycle. We report a 7-year-old, 25-kg girl with infantile-onset generali...