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Review Open access Sep 2026

Natural products as selective estrogen receptor modulators in depression-related disorders: Balancing antidepressant efficacy and safety.

Depression-related disorders remain major clinical challenges, and increasing evidence suggests that estrogen receptor (ER) signaling is involved in processes relevant to depression, including neuroinflammation, synaptic plasticity, neurotransmission, and stress regulation. Natural products and Traditional Chinese Medi...

Rong Chen, Jie Luo, Ke He et al. · 0 citations

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