Author

Ke Jiang

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#diffusion models Open access Sep 2026

Mortality-trained MRI brain age acceleration mediates sex-specific associations between health-related phenotypes and incident dementia

Brain age acceleration (BAA) has emerged as a promising neuroimaging marker of brain health and neurodegeneration. However, most existing brain age models are trained to predict chronological age, which may not be the most clinically relevant target. In this study, we instead developed a brain age model trained o...

Ke Jiang, Lei Lin, Tao Zhang et al. · Journal of Translational Med... · 0 citations

Open access Aug 2026

Metabolic Profiling of Epigenetic Aging and Its Associations With Aging‐Related Phenotypes and Modifiable Lifestyle Factors

These five metabolic signatures of epigenetic age acceleration (EAA) exhibited significant associations with aging‐related phenotypes including higher disease risk, poorer health status, and adverse clinical indicators including Gallstones, chronic kidney disease, and hepatitis.

Xun-Ying Zhao, Tian-Pei Ma, Mao-Yao Xia et al. · Aging Cell · 0 citations

Aug 2026

Metabolomic Profiling of Telomere Length: Associations with Aging-related Phenotypes and Modifiable Lifestyle Factors in Chinese Older Adults.

The Met-TL may serve as a promising biomarker of cellular aging, particularly in identifying liver dysfunction, facilitating the development of personalized aging monitoring and anti-aging intervention strategies.

Tian-Pei Ma, Xun-Ying Zhao, Ke Jiang et al. · The journals of gerontology.... · 0 citations