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Author

Ke-Ke Wang

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Review Open access Oct 2026

Cancer-associated fibroblasts: origins, functional heterogeneity and therapeutic potential

Cancer-associated fibroblasts (CAFs) are integral components of the tumor microenvironment (TME) and are increasingly recognized as critical regulators of nearly every hallmark of cancer. Once viewed as a uniform, protumorigenic cell type, it is now clear that CAFs comprise a spectrum of dynamic and plastic functional...

Li-Ting Zhou, Meng-Yue Tang, Ke-Ke Wang et al. · 0 citations

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