Author

Ke-Liang Wu

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Open access Oct 2026

scTHREAD: a cell-resolved long-read transcriptome database with linked isoform, poly(A), junction, and allelic evidence.

Cell-resolved transcript structures are essential for understanding how isoform usage, alternative polyadenylation, and allelic expression vary across cell types. However, existing single-cell long-read datasets remain fragmented across studies, platforms, species, and workflows, hindering comparison and reuse. Here, w...

Zhi-Can Fu, Ye-Lian Yan, Chun-Chun Wu et al. · Nucleic Acids Research · 0 citations

Open access Jul 2026

Full-length transcriptomic profiling reveals age-associated isoform remodeling and altered coding potential in the mouse ovary.

Ovarian aging is marked by a progressive diminution of oocyte quality and quantity, and long-read sequencing improves isoform-level resolution of ovarian transcriptomic diversity and identifies candidate aging-associated transcript alterations that may be relevant to reproductive decline.

Haiyang Wu, Xiaoyu Yin, Min Zhang et al. · Journal of Ovarian Research · 0 citations