Ke-Qi Xu

Gestational cadmium exposure is associated with dysregulated HIF-1α/Parkin-mediated mitophagy: implications for fetal growth restriction.

INTRODUCTION Cadmium (Cd) is an environmental toxicant associated with fetal growth restriction (FGR). However, the molecular mechanism underlying Cd-associated placental dysfunction remains incompletely understood. This study investigated whether altered mitochondrial quality control involving HIF-1α and Parkin contri...