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Author

Kequan Chen

2 papers indexed here

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Sep 2026

Unraveling Cadaverine Toxicity Effect to Guide the Engineering of Robust Strain.

End-product inhibition represents a major challenge in the microbial synthesis of various value-added chemicals. Cadaverine, a key monomer for polyamide synthesis, exhibits severe cytotoxicity, limiting its high-titer biosynthesis. Here, transcriptomic analysis and genome-wide library screening were integrated to syste...

Yang Liao, Si-Yuan Gao, Jiao Feng et al. · 0 citations
Open access Aug 2026

Systems-level analysis of 1,6-hexanediol stress response and tolerance engineering in Escherichia coli

This study demonstrates that 1,6-HDO exhibited strong inhibitory effects on Escherichia coli, reducing the maximum OD600 to approximately 50% of the control level under 10 g/L stress and identifies key determinants contributing to tolerance.

Xin-Yi Zhang, Lisha Qin, Hongxu Li et al. · 0 citations

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