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Author

Ke-Xin Guo

2 papers indexed here

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Open access 2026

Arterial origin-dependent susceptibility of vascular smooth muscle cells to prelamin A-induced senescence and rescue by umbilical artery-derived decellularized extracellular matrix.

OBJECTIVES To determine whether prelamin A (PLA) induces distinct senescence responses in vascular smooth muscle cells (VSMCs) from different arterial origins and whether the extracellular matrix (ECM) modulates these effects. METHODS PLA expression was examined in renal arteries from age-matched patients (59-63 year...

Ke-Xin Guo, Qun Wan, Zhi-Wei Li et al. · 0 citations
Open access Sep 2026

Cinnamaldehyde-loaded gold nanobipyramids for dual-amplification of oxidative stress to enhance cancer catalytic therapy.

Various inorganic nanozymes have been developed to generate highly reactive hydroxyl radicals (˙OH) through enzyme-mimetic catalytic activity for applications in catalytic therapy. However, the elevated levels of the antioxidant glutathione (GSH) in tumor cells can effectively neutralize ˙OH, thereby diminishing the th...

Ting Yin, Yi-Xin Wang, Ming-Yuan Li et al. · 0 citations

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