Review
Open access
Aug 2026
Multi-omics integration in malignant pleural mesothelioma: from molecular evolution and immune ecosystems to precision therapy
Malignant pleural mesothelioma (MPM) exhibits substantial molecular and cell-state heterogeneity, together with marked spatial variation in its immune and stromal microenvironment. Histological classification and individual biomarkers alone cannot adequately explain its evolution or heterogeneous treatment responses. T...
Hongmei Li, Kunzhong Zhou, Ruiting Xu et al.
· Frontiers in Oncology · 0 citations