Multifaceted renoprotection by SMTP-44D in diabetic nephropathy: Targeting inflammation, oxidative stress, and insulin resistance.
Diabetic nephropathy (DN) is a major complication of diabetes and a leading cause of dialysis initiation. However, treatment options for DN are currently limited, highlighting the urgent need for novel therapies. The pathogenesis of DN involves persistent chronic hyperglycemia and advanced glycation end products, leadi...