Open access
Jul 2026
Genetic landscape features associated with PD-L1 expression status in advanced lung adenocarcinoma: a targeted sequencing analysis
This study delineates distinct genomic landscapes associated with PD-L1 expression, suggesting PD-L1-positive status is linked to an immune-active, kinase-signaling-driven phenotype with mutually exclusive drivers, and PD-L1-negative status correlates with a more immunosuppressive, co-mutation-prone, metabolism-oriente...
Mu-Kun Huang, Zhongqiang Yao, Hua Zhang et al.
· Frontiers in Oncology · 0 citations