PDZD11 as a Potential Mediator of Radioresistance in HPV-Negative HNSCC: Implications for Adherens Junction and Calcium Signaling
Radioresistance (RR) drives treatment failure in head and neck squamous cell carcinoma (HNSCC), especially in HPV-negative subtype lacking targeted therapies. This study investigates the role of the scaffold protein PDZ Domain Containing 11 (PDZD11) in driving this resistant phenotype. Integrative bioinforma...