Author

Kelly P. Cosgrove

2 papers indexed here

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Open access Oct 2026

Stress-induced dorsal striatal dopamine release is associated with changes in functional connectivity to the prefrontal cortex in nicotine-dependent individuals—a preliminary report

The neural mechanism linking stress to addiction pathophysiology remains unclear. A proposed pathway involves stress-induced dopamine (DA) transmission impairing inhibitory control, leading to relapse. Lipopolysaccharide (LPS), a biological stressor inducing systemic inflammation, amplifies DA release. Our prior st...

Si-Yan Fan, Su Jin Kim, Y. Zakiniaeiz et al. · Frontiers in Neuroscience · 0 citations

Open access Aug 2026

Preliminary evidence of neuroimmune system disruption in opioid use disorder: Findings from a pilot PET TSPO imaging study

Background Preclinical and postmortem human studies demonstrate significant opioid-related alterations in the neuroimmune system. However, studies investigating the neuroimmune system in living people with opioid use disorder (OUD) are lacking, thereby motivating this pilot study. Methods Individuals with OUD (n = 6; D...

E. Woodcock, D. Matuskey, Yi-Yun Huang et al. · Brain, Behavior, & Immunity... · 0 citations