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Author

Kelly T. Hughes

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Open access Oct 2026

Native pathogen-phage networks reveal multilayered defense and gut-active anti-phage immunity.

Bacteriophages drive pathogen evolution, yet the mechanisms governing phage susceptibility in native bacterial backgrounds, and their consequences within mammalian hosts, remain poorly understood. Here, we mapped >1,000 interactions between 20 diverse Salmonella isolates and 52 wild phages from global disease reservoir...

Benjamin X. Wang, R. Narasimhan, A. Brady et al. · 0 citations
Open access Aug 2026

The cost-benefit trade-off of peritrichous flagellation in bacteria

A quantitative cost-benefit model is supported in which heterogeneous, spatially structured environments favor an intermediate number of flagella by balancing motility benefits against the biosynthetic costs of building and operating multiple flagella.

María Giralt-Zúñiga, Michael Jahn, Joshua L. Franklin et al. · 0 citations
Open access Aug 2026

FlgJ cell-wall hydrolyzing activity enhances, but is not required, for flagellum assembly in Salmonella enterica

Salmonella can assemble functional flagella, even when the acetylglucosaminidase activity of FlgJ is genetically inactivated, showing that early steps in flagellar assembly are more diverse than previously thought and that differences in cell wall structure between gram-positive and -negative bacteria likely determine...

Yann H. U. Chevance, M. Kinoshita, F. Chevance et al. · 0 citations

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