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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

Ken Yamada

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Review Open access Sep 2026

Nucleic acid therapeutics in neurodegenerative disorders: emerging technologies and clinical landscape

Neurodegenerative disorders have diverse etiologies from monogenic mechanisms such as toxic gain-of-function mutation in subsets of amyotrophic lateral sclerosis (ALS) to multifactorial cascades exemplified by Alzheimer’s disease (AD), which feature proteostasis failure, neuroinflammation, mitochondrial dysfunction, or...

Masahiro Ohara, S. Ishigaki, Jonathan K. Watts et al. · 0 citations
Aug 2026

Challenges and advances for metabolically stabilizing siRNA

How nuclease susceptibility, chemical modification patterns, and tissue‑specific factors influence siRNA stability and efficacy is examined, to guide the rational design of next‑generation siRNA therapeutics with improved metabolic stability and clinical performance.

Theodore‑Carrigan Broda, Ken Yamada · 0 citations

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