Author

Kena Ihle

2 papers indexed here

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Open access Sep 2026

The Landscape of Tumor Dissemination in Leptomeningeal Disease: Mapping CTC Plasticity and Regional Heterogeneity Across Blood and CSF Compartments

Background/Objectives: Leptomeningeal disease (LMD) is among the most severe complications of metastatic breast cancer, with median survival measured in weeks. Definitive diagnosis relies on neuroimaging and cerebrospinal fluid (CSF) cytology, which carries a false-negative rate of 40–50% at a single lumbar puncture. I...

Stephanie N. Shishido, Baishali Chaudhuri, Vidur Mushran et al. · Cancers · 0 citations

Open access Aug 2026

T cells are critical for pre-metastatic niche formation through the STAT3/IL-17 axis

Abstract Background Pre-metastatic niches composed of mainly myeloid cells are recognized as critical for tumor metastasis. However, whether adaptive immune cells also play an important role in pre-metastatic niche formation remains to be explored. Methods CD4+ T cell accumulation in tumor-free lung tissues from mice b...

Maciej Kujawski, Antons Martincuks, M. Song et al. · Journal for ImmunoTherapy of... · 0 citations