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Author

Kenneth A. Marx

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Open access Aug 2026

Kinetics, thermodynamics, and mechanisms of PMO interactions from computational molecular modeling

Using solution viscosity measurements combined with computational molecular modeling, interactions of therapeutic 22-mer, 25-mer, and 30-mer PMOs in concentrated solutions are explored, identifying weak preferential functional group interaction patterns that underlie thermodynamic stability.

Ying Chou, Igor Novikov, Daniel Pierson et al. · 1 citation

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