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Author

Kerstin Otte

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Open access Aug 2026

Expanding Transposase Technology to Regulatory Noncoding RNAs for Stable Expression in CHO Cells

A transposase‐mediated platform for stable microRNA (miRNA) expression in CHO cells is established and the first application of a DNA transposon system for long‐term miRNA genome integration is demonstrated, demonstrating the applicability of transposase systems beyond protein‐coding transgenes.

Sonja Lochmueller, Linus Weiss, Kerstin Otte · 0 citations
Open access Jul 2026

Engineering Stable Lentiviral Vector Producer Cells Improves LVV Production.

The results demonstrate that transcriptomics-guided host-cell engineering is an effective strategy to identify and relieve intrinsic bottlenecks in stable LVV producer cell lines.

Jona Röscheise, Lena-Marie Eberle, Holger Laux et al. · 0 citations

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