Synthesis, antimicrobial activity and in silico studies of novel sulfonamide-benzothiazole conjugate compounds
The emergence of multidrug-resistant pathogens and polymicrobial infections underscores the urgent need for novel broad-spectrum antimicrobial agents. In this study, a series of sulfonamide–benzothiazole conjugates (4a–4j) were synthesized via a straightforward, scalable route employing thioamide formation, nucleophili...