BACKGROUND
Alcohol-associated liver disease (ALD) is a major cause of morbidity, yet therapies for severe inflammation remain limited.
OBJECTIVE
We examined whether circulating and hepatic immunoglobulin A (IgA) and hepatic myeloid-cell IgA binding are associated with interleukin-1 beta (IL-1β)-linked inflammation an...
Min Gu Kim, K. Tak, D. Seo et al.· Gut· 0 citations
Background/purpose Atezolizumab–bevacizumab (AB) and durvalumab–tremelimumab (DT) are standard first-line therapies for unresectable hepatocellular carcinoma (uHCC), but their comparative effectiveness remains uncertain. Methods We included 76 observational reports comprising 10,243 patients. Report-level median surviv...
Jongin Lee, K. Tak, Hee Sun Cho et al.· Frontiers in Immunology· 0 citations
Tea is a widely consumed plant-derived beverage with potential metabolic and vascular effects, but its prognostic dose–response relationship in metabolic dysfunction-associated steatotic liver disease (MASLD) remains unclear.
We analyzed 360,548 UK Biobank participants, including 169,241 individuals with MAS...
Tom Ryu, Jaejun Lee, Ji Won Han et al.· Frontiers in Nutrition· 0 citations
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