Author

Kevin A. Keay

2 papers indexed here

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Review Open access Nov 2026

Brain sites involved in endogenous analgesia

Abstract Pain modulation is a fundamental survival mechanism that prioritises, shapes, and suppresses nociceptive inputs to optimise behaviour. Although acute pain signals potential or actual tissue damage, sustained pain can impair essential behaviours, necessitating modulatory circuits that dynamically regulate nocic...

Luke A. Henderson, L. Crawford, James W. M. Kang et al. · Pain · 0 citations

Open access Sep 2026

Regional brain structural changes during the transition from acute to chronic neuropathic pain: a longitudinal study in a rat model of orofacial pain.

Brain imaging studies have identified structural alterations in individuals with chronic neuropathic pain, particularly in regions involved in sensory, emotional, and cognitive processing. However, most studies remain cross-sectional, leaving the temporal progression of these changes during pain chronification unclear....

Angela Doshen, L. Crawford, James W. M. Kang et al. · Journal of Neuroscience · 0 citations