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Sep 2026

Abstract PR008: Oligodendrocyte-secreted factor L-PGDS potentiates phagocytosis of tumor-associated myeloid cells in pediatric high-grade gliomas

Pediatric brain tumors are the most common solid tumors in children. Pediatric high-grade gliomas (pHGGs) account for approximately 17% of brain tumors in children aged 0–14 years and remain largely incurable. Immunotherapies, including immune checkpoint blockade, have shown minimal benefit in pHGGs, largely due to i...

Kevin Hu, Emily Zhang, Wei-Yi Peng et al. · 0 citations

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