Curcumin attenuates α-synuclein pathology in Parkinson’s disease model mice through modulation of UBC9-associated SUMOylation signaling
It is demonstrated that curcumin exerted neuroprotective effects in a PD model by attenuating α-syn pathology and identifying UBC9-mediated SUMOylation as a potential target for curcumin and highlighting a promising strategy for modifying α-syn-associated pathology in PD.