Jul 2026
Design, robust synthesis, and anti-liver cancer activity of 2-hydrazono-5-acetyl-[1,3,4]thiadiazole and N'-ethylideneethanethiohydrazide derivatives: In vitro, gene expression, DNA damage, and DNA fragmentation.
A novel series of 2-hydrazono-5-acetyl-[1,3,4]thiadiazole and N'-ethylideneethanethiohydrazide derivatives tested as anticancer agents against a panel of cancer cell lines, and the mechanism of action of the most active compounds against liver cancer was explored through gene expression, DNA damage, and DNA fragmentati...
Ashraf A. Sediek, Eman Sabry, Huda F. Khalil et al.
· Bioorganic chemistry (Print) · 0 citations