Viral therapy requires effective control of intracellular viral replication while limiting harmful host responses that may contribute to disease progression and complications. Thymoquinone (TQ), a major bioactive constituent of Nigella sativa, has potential antiviral and host-protective properties, but its therapeutic...
M. A. Khan, M. Khan, Khaled S. Allemailem· Biomolecules· 0 citations
Background: Thyroid dysfunction can affect erythropoiesis and red blood cell indices; however, reports on anemia patterns among Saudi women remain insufficient. This study investigated hematological alterations and anemia morphology in euthyroid, hypothyroid, and hyperthyroid women. Methods: A retrospective cross-secti...
A. Mackawy, Ayshah Saleh H. Alorini, Khaled S. Allemailem et al.· Life· 0 citations
Network pharmacology examines drug action across interacting targets, pathways, and disease modules. Increasingly, however, the graph neural networks and knowledge-graph models used for this purpose are difficult to inspect. This critical narrative review considers feature attribution, attention, counterfactual and rul...
Khaled S. Allemailem, A. Almatroudi, Abdullah M. Alnajim· International Journal of Mol...· 0 citations
Background/Objectives: Streptococcus suis is an important zoonotic pathogen responsible for severe infections in animals and humans, and the emergence of diverse strains has reduced the effectiveness of conventional antimicrobial therapies. Since there is no broadly protective vaccine, there is a need for new vaccinati...
N. S. Alhaggass, Waad A. Aljohani, Reem Alromaihi et al.· Pharmaceuticals· 0 citations
The findings suggest that N. sativa may provide dual therapeutic benefits by modulating host immune responses and targeting pathogen proteins, supporting its potential for future anti-sepsis drug development based on computational predictions that require experimental validation.
Kinza Alamgir, Sher Muhammad, Muhammad Shahid et al.· Scientific Reports· 0 citations
An integrated reverse vaccinology strategy is used to identify conserved immunogenic regions from the Envelope protein and NS5 protein, and construct a multi-epitope vaccine for Usutu virus, predicting enhanced humoral and cellular immune-response patterns following repeated antigen administration.
Reem A. Alromaihi, H. Alharbi, S. Almerdasi et al.· Microorganisms· 0 citations
Findings suggest that Bay9 has potential as a biocontrol agent against P. versicolor under laboratory, detached-leaf, and semi-controlled greenhouse conditions, and further studies are required to elucidate the underlying molecular mechanisms and to validate its efficacy under field conditions before practical applicat...
Ezzeldin Ibrahim, Raghda Nasser, Doaa A. Kafsheer et al.· BMC Plant Biology· 1 citation
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