Author

Khalid Mohammed Khan

2 papers indexed here

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Sep 2026

Synthesis and Biological Evaluation of Imidazo‐Thiadiazole‐Linked Benzisoxazole Hybrids as Dual α ‐Glucosidase and α ‐Amylase Inhibitors With Antioxidant Potential

Type 2 diabetes mellitus (T2DM) remains a major global health challenge, necessitating the discovery of novel therapeutics with improved safety and efficacy. In this study, a series of imidazo‐thiadiazole‐linked benzisoxazoles ( 1–20 ) was synthesized and evaluated for dual inhibitory activity against α ‐glucos...

Mehwish Solangi, Komal Solangi, M. Özil et al. · ChemistrySelect · 0 citations

Open access Aug 2026

Design and synthesis of quinoline-derived thioureas as potential antihyperglycemic, anti-Alzheimer, and antioxidant agents

A library of quinoline-based thiourea hybrids 1–41 was synthesized via a single-step reaction scheme. All compounds were evaluated for their inhibitory potential against α-amylase, α-glucosidase, AChE, and BChE enzymes as well as for DPPH radical scavenging activity. Among forty-one compounds, 27–31 and 33–37 showed ex...

Faiza Seraj, Maryam Maqbool, F. Ali et al. · RSC Advances · 0 citations