Khalilah E. Taylor

Abstract A047: Mechanistic dissection and inhibitor targeting of nutrient scavenging in pancreatic cancer

Mutational activation of the KRAS oncogene occurs in over 90% of pancreatic ductal adenocarcinoma (PDAC) patients, and plays a crucial role in tumor initiation, progression, and tumor maintenance. Historically considered undruggable, there has recently been a surge in efforts to develop and improve drugs that target...