Open access
Sep 2026
Exploring a DNA methylation field effect in renal cell carcinoma and its implications for biomarker research
A field effect, the phenomenon of molecular alterations, such as DNA methylation, in normally appearing tissue surrounding a malignant tumor, has been suggested to be associated with malignant transformation. Nevertheless, normally appearing tissue adjacent to the tumor is frequently used as control tissue in biomarker...
K. Lommen, Jaycey F. Kelly, I. Samarska et al.
· Epigenetics Communications · 0 citations