Open access
Sep 2026
The effects of fentanyl and dexmedetomidine on cardiorespiratory activity: implications for morbidity and mortality associated with adulterated fentanyl products
Introduction A recent driver of opioid-related overdose deaths has been the adulteration of illicitly manufactured fentanyl with alpha-2 (α2)-adrenergic agonists; however, little research has examined their toxicity when combined with fentanyl. The purpose of this study was to examine the effects of fentanyl and the α2...
Mark A. Smith, E. Thomas, Stephanie G. Hockett et al.
· Frontiers in Pharmacology · 0 citations