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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Klára Nováková

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Review Open access Aug 2026

Polygenic risk score and its role in cancer susceptibility.

BACKGROUND Polygenic risk score (PRS) has the ability to stratify inherited susceptibility to cancer and, as a complement to monogenic testing, can identify individuals at increased genetic risk even when no pathogenic variant is detected in high- or moderate-penetrance genes. It reflects the combined additive effects...

Adéla Mišove, E. Macháčková, Klára Nováková et al. · 0 citations

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