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Open access Sep 2026

Amyloid-Independent Elevation of Plasma phosphorylated tau-217 Tracks Neurodegenerative Risk in Tuberous Sclerosis Complex: Implications for mTOR-Targeted Intervention

A novel link between TSC and AD that substantiates shared downstream neurodegenerative pathways is suggested and the potential utility of ptau-217 as a minimally invasive biomarker for TAND severity, neurodegenerative risk, and AD-like prognosis in TSC is supported and as a tool to guide new mTOR-targeted therapeutic s...

J. Baumel, M. Lutz, C. Ding et al. · 0 citations

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