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Author

Ko-Hsiu Lu

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2 papers indexed here

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Review Sep 2026

Flavones in osteosarcoma: Molecular mechanisms, antitumor activity, and translational challenges.

Osteosarcoma remains the most common primary malignant bone tumor, and survival has improved little over recent decades because of metastasis and therapeutic resistance. Flavones exhibit diverse anti-osteosarcoma activities by suppressing proliferation, inducing apoptosis, ferroptosis and autophagy, inhibiting metastas...

Ko-Hsiu Lu, Renn-Chia Lin, Meng-Ying Tsai et al. · 0 citations
Open access Aug 2026

Tricin Inhibits Human Osteosarcoma Cell Metastasis via Suppression of ZNF503 and the PI3K–PIP3–Akt Pathway

Osteosarcoma is the most common primary malignant bone tumor and is associated with a high mortality rate due to its pronounced metastatic potential. Although tricin has been proposed as a chemosensitizer in various malignancies, its anti‐metastatic effect in osteosarcoma remains poorly characterized. This study invest...

Chia-Hsuan Chou, Jia-Sin Yang, Pei-Ni Chen et al. · 0 citations

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