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Kobra Tayyari

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Case report Open access Jul 2026

Inter-chromosomal Effect in a Robertsonian Translocation (13;14) Carrier with a Child Affected by Down Syndrome: A Case Report

Background: Although the balanced carriers of Robertsonian translocations (ROBs) typically exhibit normal phenotypes, they may experience recurrent abortions or have offspring with chromosomal disorders. A proposed mechanism is the inter-chromosomal effect (ICE), where disrupted meiotic segregation may increase aneuplo...

Sahra Sahraeean, Asiyeh Jebelli, Saeed Ghadimi Haddadan et al. · 0 citations

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