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Author

Koji Matsuhisa

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Open access Sep 2026

Cholesterol maintains the degradative capacity of lysosomes during clearance and recycling of dysfunctional mitochondria

Efficient clearance and recycling of dysfunctional mitochondria through the robust catabolic activity of lysosomes are essential for cellular health. However, how membrane lipids contribute to maintaining the degradative capacity of lysosomes remains poorly understood. Here, we show that cholesterol plays a critical ro...

Hao-Ning Yang, Koji Matsuhisa, Meng Wei et al. · 0 citations

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